VZV Foundation - A Decade Of Leadership In The Fight Against VZV Infections

	Oral Presentation Abstracts: 65 [65] UITRASTRUCTURAL STUDY ON THE HOST RELATIONSHIP AND AFFINITY BETWEEN VZV AND DIFFERENT CELLS IN LESIONS OF PATIENTS WITH VARICELLA AND HERPES ZOSTER Meng Qiang Epidemic Prevention Station of Henan Province, zhengzhou, P.R.China To study the host relationship and affinity between the varicella-zoster virus (VZV) and various kinds of cells in the lesion, the skin lesions of varicella and herpes zoster were observed with transmission electron microscope. The results showed that the host cells of VZV were of different kinds, which included epidermal cells, fibroblasts, endothelial cells and pericytes of the blood vessels in the dermis, Schwann's cells, macrophages and mast cells. Among them,the affinity of VZV with epidermal cells and fibroblasts was the strongest, and no host relationship with neutrophils and lymphocytes was found. The neutrophils showed an obvious phenomenon to phagocytose and digest VZV, and the macrophagea had role both in defending and spreading the viruses. Meng Qiang, Epidemic Prevention Station of Henan Province 47 Wei wu street 450003 zhengzhou, P.R.China

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UITRASTRUCTURAL STUDY ON THE HOST RELATIONSHIP AND AFFINITY BETWEEN VZV AND DIFFERENT CELLS IN LESIONS OF PATIENTS WITH VARICELLA AND HERPES ZOSTER

*Meng Qiang
Epidemic Prevention Station of Henan Province, zhengzhou, P.R.China

To study the host relationship and affinity between the varicella-zoster virus (VZV) and various kinds of cells in the lesion, the skin lesions of varicella and herpes zoster were observed with transmission electron microscope. The results showed that the host cells of VZV were of different kinds, which included epidermal cells, fibroblasts, endothelial cells and pericytes of the blood vessels in the dermis, Schwann's cells, macrophages and mast cells. Among them,the affinity of VZV with epidermal cells and fibroblasts was the strongest, and no host relationship with neutrophils and lymphocytes was found. The neutrophils showed an obvious phenomenon to phagocytose and digest VZV, and the macrophagea had role both in defending and spreading the viruses.

*Meng Qiang, Epidemic Prevention Station of Henan Province 47 Wei wu street 450003 zhengzhou, P.R.China